|Eurycoma longifolia jack 'Tongkat Ali' has been used to improve male virility and sexual prowess as part of ongoing cultural tradition.|
demonstrates a scientific basis for its historical use due to the plants
levels can prove to be highly beneficial for men suffering the effects
of lowered hormone levels.
Tongkat ali Eurycoma longifolia Jack commonly has been successfully used in southeast Asia for generations to increase male virility and sexual prowess. The roots are the most valuable component and are used for the treatment of aches, persistent fever, malaria, sexual insufficiency, dysentery, glandular swelling, and as health supplements. Root extract of the plant have been administered for restoring energy and vitality, enhancing blood flow and functioning as a herbal ingredient for women after child birth.
Plaplai Plueak aka: 'Tongkat ali' (Eurycoma
Flavonols: Quercetin, Myricetin and Kaempferol.
Canthin-6-one alkaloids, -ß- carboline alkaloids, quassinoids, quassinoid diterpenoids,
Eurycomaoside, tirucallane-type triterpenes, squalene derivatives, biphenylneolignans,
eurycolactone, laurycolactone, and eurycomalactone.
Heller CG, Myers GB.
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with angina. Int J Impot Res. 2007 Mar-Apr;19(2):176-82. Epub 2006 Aug 31.
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Schottner M, Gansser D, Spiteller G, et al. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med 1997;63:529-32.
Hyrb D et al. The effect of extracts of the roots of the stinging nettle (Urtica dioca) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Med, 1995, 61:31-32.
Konrad L, Muller HH, Lenz C, et al. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Med 2000;66:44-7.
Lichius JJ, Muth C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Planta Med 1997;63:307-10.
Durak I, Biri H, Devrim E, et al. Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Cancer Biol Ther 2004;3:855-7.
Kassen A, Berges R, Senge T, et al. Effect of beta-sitosterol on transforming growth factor-beta-1 expression and translocation protein kinase C alpha in human prostate stromal cells in vitro. Eur Urol 2000;37:735-41.
Berges R, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet. 1995;345:1529-32.
Klippel K, et al. A multicentric placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. German BPH-Phyto Study Group. Br J Urol. 1997; 80:427-32.
Shimoi K, et al. Intestinal absorption of luteolin 7-O-beta-glucoside in rats and humans. FEBS Lett. 1998;438:220-24.
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Saarinen N et al. No evidence for the in vivo activity of aromatase-inhibiting flavonoids. J Steroid Biochem Mol Biol 2001, 78:231-39.
Ang HH, Cheang HS, Yusof AP. Effects of Eurycoma longifolia Jack (Tongkat Ali) on the initiation of sexual performance of inexperienced castrated male rats. Exp Anim 2000;49:35-8.
Ang HH, Ikeda S, Gan EK. Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia Jack. Phytother Res 2001;15:435-6.
Ang HH, Sim MK. Eurycoma longifolia Jack enhances libido in sexually experienced male rats. Exp Anim 1997;46:287-90.
Matsuda H, et al. Anti-androgenic activity of Myricae cortex-Isolation of active constituents from bark of Myrica rubra. Biol Pharm Bull. 2001; 24:259-63.
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Debing E, et al. Men with atherosclerotic stenosis of the carotid artery have lower testosterone levels compared with controls. Int Angiol. 2008 Apr;27(2):135-41.
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